National Academies:

New Heroes

Alia Crum

Dr Alia Crum arrived in the soft brightness that comes after a storm. The air outside Stanford’s Psychology Building was cool and clear, the kind of light that makes everything feel freshly washed. She settled into a comfortable chair in her office with an easy calm, as if the morning’s weather had cleared a little space around her too.

Crum is a psychologist who studies something deceptively simple. She examines how beliefs shape physiology. Not in the loose mystical way that phrase sometimes gets tossed around. Her work cuts closer to the bone. The body is not a passive machine. It responds to expectation. It listens to mindset. She has built a career showing that what we think about stress, food, exercise, illness and treatment can tilt the body’s response in measurable ways.

Her early work came out of a moment most of us would ignore. While studying stress at Yale she realized that stress itself was not always the enemy. The fear of stress could be worse. The belief that stress is damaging primes the body to show more harmful patterns. The belief that stress can sharpen performance nudges the system toward resilience. Not wishful thinking. Observable biology. Shifts in cortisol. Changes in blood vessel constriction. A different hormonal conversation between mind and body.

One of her most famous studies grew from that instinct to question the obvious. The milkshake experiment has been told and retold because of how blunt and beautiful it is. Crum and her team gave participants a milkshake. Same ingredients. Same calories. Same everything. But the label was switched. For one group it was described as a rich decadent indulgence. For the other it appeared as a restrained sensible shake. People drank it while their hunger hormones were measured. Ghrelin the hormone that pushes hunger up or down behaved as if the labels were real. The decadent shake triggered a steep drop in ghrelin as though the body believed satisfaction had arrived. The restrained shake left ghrelin high as though the body had been shortchanged. The stomach listened not just to what was swallowed but to the story around it.

Crum leans into these contradictions. The world is overflowing with advice about how to treat your body. She keeps asking how the body treats belief. Her research at the Mind and Body Lab explores placebos, treatment expectations, the power of framing and how subtle shifts in context can rewrite physiology. People heal faster when they think a treatment is potent even if the medication is identical. Housekeepers who were told their daily work counted as exercise showed improvements in weight and blood pressure without any change in actual workload. Mindset became part of the treatment itself.

Talking with her you sense someone who has not grown cynical despite years of studying human perception. She seems fascinated by how easily the mind can box itself in and how quickly it can step out again with the right nudge. During the shoot she often rested her hand on a notebook the way some people hold a compass. These experiments begin as questions scribbled on a page before they grow into protocols, measurements and data sets that surprise the field again and again.

There is a warmth to the way she listens. She gives every idea a moment to breathe before responding. It makes sense. Her whole scientific life is built on the idea that thoughts matter. Beliefs matter. Not in a magical way. In a biological way. You walk out of her lab with the unsettling and oddly hopeful sense that the stories we tell ourselves are not just background noise. They seep inward. They shape the body. They set the terms for how we cope with stress, how we move through illness and how we meet our own expectations.

Photographing her on that quiet afternoon at Stanford felt like brushing up against the edge of a much larger truth. The mind is not sealed off from the body. Crum has spent her career proving it. And she is only getting started.


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